Ductus venosus pulsatility index measurement reduces the false-positive rate in first-trimester screening

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Ductus venosus pulsatility index measurement reduces the false-positive rate in first-trimester screening.

OBJECTIVE To investigate if ductus venosus (DV) pulsatility index for veins (PIV) and a-wave measurements can increase the accuracy of first-trimester Down syndrome screening in a high-risk population. METHODS The database of our fetal medicine unit was searched for all cases at increased first-trimester Down syndrome risk. Multivariable logistic regression was used to construct a prediction ...

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Contribution of ductus venosus Doppler in first-trimester screening for major cardiac defects.

OBJECTIVE To determine whether assessment of ductus venosus flow at 11-13 weeks' gestation improves the detection rate of cardiac defects achieved by screening with nuchal translucency (NT) thickness. METHODS Prospective first-trimester screening for aneuploidies, including measurement of fetal NT and assessment of ductus venosus flow. The performance of different combinations of increased fe...

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A mixture model of ductus venosus pulsatility index in screening for aneuploidies at 11-13 weeks' gestation.

OBJECTIVE To assess the value of ductus venosus pulsatility index for veins (DV PIV) in screening for aneuploidies at 11-13 weeks' gestation. METHODS Fetal DV PIV was measured in singleton pregnancies undergoing first-trimester screening for aneuploidies. In euploid (n = 44,756) and aneuploid (202 cases of trisomy 21, 72 cases of trisomy 18 and 30 cases of trisomy 13) fetuses, DV PIV was best...

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Factors predicting a positive pregnancy screening test at first trimester

Background: For every pregnant woman, it is possible to have a child with chromosomal abnormalities. Although this possibility is not very high, by performing screening tests and considering the mother's background factors, we can largely realize the real extent of this possibility. Many comorbidities (like high blood pressure, diabetes, and obesity) and high-risk exposures (like alcohol consu...

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Improving our Knowledge in Twins: The Role of Ductus Venosus in the First Trimester

Ductus venosus (DV) is a tiny vessel with a central role in fetal circulation both in singletons and multiples. In the present review we detail the contribution of DV evaluation in twin pregnancies in the first trimeter of pregnancy. The higher prevalence of abnormal A-wave in fetuses with abnormal karyotype and/or cardiac defects made DV evaluation a useful marker for the screening of chromoso...

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics & Gynecology

سال: 2010

ISSN: 0960-7692

DOI: 10.1002/uog.7706